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Long-term results of sclerotherapy for cervical-thoracic-mediastinal lymphatic and venous malformations: A case

Quan-Feng Luo1

  • 1Department of Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing 100081, China.

International Journal of Surgery Case Reports
|July 21, 2022
PubMed

Insights

Sclerotherapy effectively treats rare infant cervical-thoracic-mediastinal lymphatic malformations (LVMs). This minimally invasive approach offers a low-risk, high-cure rate with no long-term developmental side effects.

Area of Science:

  • Vascular Surgery
  • Pediatric Surgery
  • Interventional Radiology

Background:

  • Cervical-thoracic-mediastinal lymphatic malformations (LVMs) in infants are rare and challenging to treat due to high risks and recurrence.
  • Infantile LVMs can cause severe symptoms like dyspnea and breathing difficulties.

Purpose of the Study:

  • To evaluate the efficacy and safety of sclerotherapy for treating complex infant LVMs.
  • To compare sclerotherapy with surgical resection for thoracic-mediastinal LVMs.

Main Methods:

  • A phased, step-by-step sclerotherapy approach using bleomycin and triamcinolone acetonide.
  • Percutaneous catheterization under B-ultrasound guidance for thoracic and mediastinal LVMs.
  • Long-term follow-up to assess recurrence and developmental outcomes.

Main Results:

  • Complete regression of submandibular and cervical LVMs.
  • Approximately 95% regression of thoracic and mediastinal LVMs.
  • No recurrence observed during an 11-year follow-up period with normal development.

Conclusions:

  • Sclerotherapy is an effective and minimally invasive treatment for infant cervical-thoracic-mediastinal LVMs.
  • Sclerotherapy presents a lower risk profile compared to surgical resection, with significant curative effects.
  • This treatment demonstrates no adverse effects on infant development.

Keywords:
BleomycinCase reportLymphatic malformationMediastinumSclerotherapyThoraxVenous malformation

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