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Multiple sclerosis and the risk of infection: Association of British Neurologists consensus guideline
Marija Cauchi1, Mark Willis2, Angela Andrews3
1Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, University Hospital of Wales, Cardiff, UK cauchim1@cardiff.ac.uk.
Abstract:
Infection in people with multiple sclerosis (MS) is of major concern, particularly for those receiving disease-modifying therapies. This article explores the risk of infection in people with MS and provides guidance-developed by Delphi consensus by specialists involved in their management-on how to screen for, prevent and manage infection in this population.
Insights
Infections pose a significant risk for individuals with multiple sclerosis (MS), especially those on disease-modifying therapies. This guidance offers expert consensus on screening, prevention, and management strategies for infections in MS patients.
Area of Science:
- Neurology
- Infectious Diseases
- Immunology
Background:
- Infection is a major concern for patients diagnosed with multiple sclerosis (MS).
- The risk of infection is heightened in MS patients undergoing disease-modifying therapies (DMTs).
Purpose of the Study:
- To explore the multifaceted risks of infection in individuals with multiple sclerosis.
- To provide evidence-based guidance for the screening, prevention, and management of infections in the MS population.
Main Methods:
- Guidance developed through Delphi consensus.
- Involved specialists actively managing patients with multiple sclerosis.
Main Results:
- Consensus reached on key aspects of infection risk assessment in MS.
- Established protocols for proactive infection prevention strategies.
- Defined approaches for effective infection management in this vulnerable group.
Conclusions:
- Comprehensive strategies are essential for mitigating infection risks in MS patients.
- Adherence to expert-guided protocols can improve patient outcomes and safety.
- This consensus provides a valuable framework for clinicians managing MS.
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