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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Related Experiment Video

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Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
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Depicting Developing Trend and Core Knowledge of Primary Open-Angle Glaucoma: A Bibliometric and Visualized Analysis.

Liting Zhao1,2,3,4, Jinfei Li1,2, Lemeng Feng1,3,4

  • 1National Clinical Research Center for Geriatric Diseases, Xiangya Hospital of Central South University, Changsha, China.

Frontiers in Medicine
|July 22, 2022
PubMed
Summary

Research on primary open-angle glaucoma is rapidly expanding, driven by an aging population. Bibliometric analysis reveals increasing publications, key research areas, and global trends in this irreversible eye condition.

Keywords:
VOSviewerbibliometrics analysiscitespaceintraocular pressureprimary open angle glaucoma

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Area of Science:

  • Ophthalmology
  • Biochemistry
  • Molecular Biology
  • General Internal Medicine
  • Pharmacology
  • Pharmacy
  • Science Technology

Background:

  • Glaucoma prevalence is increasing due to an aging population.
  • Glaucoma is an insidious and irreversible condition.
  • Primary open-angle glaucoma is the most common type of glaucoma.

Purpose of the Study:

  • To assess the current status of primary open-angle glaucoma research.
  • To analyze global trends in primary open-angle glaucoma research.
  • To identify key areas and collaborations in primary open-angle glaucoma clinical research.

Main Methods:

  • Bibliometric analysis of publications from 2000 to 2021.
  • Data retrieved from the Web of Science database.
  • Analysis conducted using VOSviewer and Citespace.

Main Results:

  • A total of 6,401 publications were analyzed.
  • Publication numbers increased from 139 in 2000 to 563 in 2021.
  • American researchers led in publications, h-index, and citations.
  • The Journal of Glaucoma published the most papers.
  • Research hotspots evolved from epidemiology to pathogenesis, diagnosis, and treatment.

Conclusions:

  • Interest and research in primary open-angle glaucoma are increasing.
  • Studies on primary open-angle glaucoma span multiple scientific disciplines.
  • The field is expanding beyond ophthalmology into related areas.