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Bone Disorders01:29

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
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Forearm Hereditary Multiple Exostosis: A Retrospective Case Series Study.

Nizar Hamdi1, Hatan Mortada2,3, Zainab Al Eid4

  • 1Departments of Surgery and Orthopedic Surgery, King Faisal Specialist Hospital & Research Centre, Riyadh, SAU.

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|July 22, 2022
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Summary

Hereditary multiple exostosis (HME) in the forearm is rare. Surgical excision is effective, with most patients experiencing no recurrence, suggesting simple radial head excision for secondary procedures.

Keywords:
benign forearm tumorsclinical experiencediaphyseal aclasisforearmmetachondromatosismultiple hereditary exostosisosteochondromassaudi arabia

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Area of Science:

  • Orthopedics
  • Genetics
  • Pediatric Surgery

Background:

  • Hereditary multiple exostosis (HME) is a rare genetic disorder causing benign bone growths.
  • Forearm involvement is common in HME, necessitating diverse treatment strategies.
  • This study represents the first investigation of HME in the Middle East and Saudi Arabia.

Purpose of the Study:

  • To analyze the clinical experience and outcomes of forearm HME surgical management.
  • To evaluate patient demographics, treatment modalities, and long-term results.
  • To contribute to the limited literature on HME, particularly in the Saudi Arabian context.

Main Methods:

  • Retrospective case review of patients with forearm HME operated between 2006 and 2022.
  • Analysis of patient demographics, clinical presentation, surgical management, and outcomes.
  • Assessment using the Masada scale and radiological evaluation for outcomes.

Main Results:

  • Ten patients (12 forearms) with HME were analyzed; average age at surgery was 12.7 years.
  • Most patients (50%) presented with Masada type 1; 50% underwent radial head resection.
  • The majority (80%) had no complications or recurrence; two cases of recurrence were noted.

Conclusions:

  • Excision of HME lesions at skeletal maturity with regular follow-up is the primary management.
  • Simple radial head excision is recommended for future secondary procedures if needed.
  • Further research is essential to optimize outcomes for pediatric HME patients due to the condition's rarity.