Related Experiment Video
Updated: Sep 4, 2025
04:09
Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices
Published on: June 13, 2025
329
A 44-year-old man with esophageal ulcer
Delvise T Fogwe1, Matthew T Ho1, Aditya S Shah2
1Department of Internal Medicine Mayo Clinic Rochester Minnesota USA.
Clinical Case Reports
|July 22, 2022
Summary
Cytomegalovirus (CMV) esophagitis can mimic other esophageal infections in immunocompromised individuals. Large, deep esophageal lesions warrant consideration for CMV esophagitis, confirmed via biopsy and immunostaining.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Oncology
Background:
- Cytomegalovirus (CMV) infections are common in immunocompromised patients.
- Esophageal lesions can present with diverse etiologies, complicating diagnosis.
Observation:
- A case of CMV esophagitis is presented, highlighting diagnostic challenges.
- Giant (>1 cm) and deep esophageal lesions were observed.
Findings:
- CMV esophagitis can be difficult to differentiate from other infectious esophageal lesions.
- Biopsy with immunostaining is the gold standard for confirming CMV esophagitis.
Implications:
- Early recognition of characteristic lesions can guide diagnostic workup.
- Accurate diagnosis of CMV esophagitis is crucial for appropriate treatment in immunocompromised hosts.
Related Concept Videos
01:26Peptic Ulcer Disease IV: Management
141
Medical treatment strategies for peptic ulcers encompass various methods. The primary goal of treatment is to diminish gastric acidity and strengthen mucosal defense mechanisms.
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
141
01:26Esophageal Strictures-II: Clinical Features and Management
155
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
155
01:30Peptic Ulcer Disease I: Introduction
274
Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
274
01:30Esophageal Strictures-I: Introduction
254
Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
254
01:21Barrett Esophagus-II: Clinical Manifestations and Management
285
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
285
01:24Esophageal Varices-I: Introduction
312
Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
312