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Genomic and immune microenvironment profiling in a case of metastatic intrathyroid thymic carcinoma
Hiroki Ishii1, Takahiro Tsujikawa2, Naoki Oishi3
1Department of Otolaryngology, Head and Neck Surgery University of Yamanashi Chuo Japan.
Clinical Case Reports
|July 22, 2022
Abstract:
Metastatic intrathyroid thymic carcinoma (ITTC) is a rare cancer with no effective drugs for controlling. This case report has shown genomic and immune microenvironment profiles in metastatic ITTC and emphasized an immunosuppression via a PD-1/PD-L1 pathway, possibly strengthening the rationale for immune checkpoint blockade as a novel treatment.

