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Management Strategies for Descending Thoracic Aortic Thrombus: A Review of the Literature
Quynh Nguyen1, Xiya Ma2, Dominique Vervoort3
1Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Insights
Descending thoracic aortic thrombus (DTAT) can cause serious embolic events. Medical management is often successful, but endovascular therapy may be needed if conservative approaches fail.
Area of Science:
- Cardiology
- Vascular Surgery
- Radiology
Background:
- Descending thoracic aortic thrombus (DTAT) is an under-recognized cause of systemic emboli.
- DTAT can lead to catastrophic embolic consequences.
- Current guidelines for DTAT management are lacking.
Purpose of the Study:
- To review the clinical presentation of DTAT.
- To examine diagnostic methods and findings for DTAT.
- To evaluate outcomes of various treatment options for DTAT.
Main Methods:
- Systematic review of existing literature.
- Analysis of clinical presentation, diagnostic imaging, and treatment outcomes.
- Comparison of medical and endovascular treatment approaches.
Main Results:
- Medical management is the most common initial approach for DTAT.
- Medical management reports a high success rate.
- Endovascular therapy is an option for thrombus exclusion if conservative management fails.
Conclusions:
- DTAT requires further recognition and research.
- A multimodal approach to DTAT diagnosis and management is essential.
- Treatment strategies should be individualized based on patient presentation and risk stratification.
Abstract:
Descending thoracic aortic thrombus (DTAT) is an under-recognized source of systemic emboli with potential catastrophic consequences. Imaging modalities such as echocardiography, computed tomography, magnetic resonance imaging, and angiography can help identify and characterize the extent of embolic events. Established guidelines regarding the management of DTAT are currently lacking. Multiple treatment modalities are available; however, the effectiveness of each approach remains to be determined. In this study, we performed a review to examine the clinical presentation, diagnostic methods and findings, and outcomes of various treatment options for patients with DTAT. Medical management is the least invasive and most frequently chosen initial approach, offering a high reported success rate, whereas endovascular therapy can have a role in thrombus exclusion should conservative management fail.
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