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Wound healing activity of topical herbal aerosol sprays on diabetic and Varicose Ulcers: A randomized, controlled,
Sanjay Tamoli1, Vijay Ukhalkar2, G Shrinivas Acharya3
1Director, Target Institute of Medical Education & Research, 402/A, Jaswanti Allied Business Park, Ramchandra Lane Extn, Malad West, Mumbai, 400064, India.
Background:
Panchavalkala Kwatha and Jatyadi Taila are recommended for cleaning and healing of non-healing ulcers such as Diabetic Foot Ulcer (DFU) and Varicose Ulcers (VU).
Objectives:
Innovative topical aerosol sprays viz. Panchavalkala Kwatha Aerosol Spray (PKS) and Jatyadi Taila (Healz) Aerosol Spray (JTS) were evaluated for healing in DFU & VU against conventional treatment.
Materials & Methods:
After obtaining approval from Ethics Commitees & informed consent, 53 patients were randomized in two study groups. In one group, ulcer cleaning was done with PKS and then JTS was used for dressing while in other group, cleaning was done with Hydrogen peroxide and/or Hypochlorite followed by dressing with 10% Povidone iodine. Ulcer examination was done from baseline to every 7th day by Bates Jensen ulcer assessment tool, digital photographs and photographic ulcer assessment tool. Comparison of categorical variables was done using t-test.
Results:
The dual action of PKS and JTS exhibited potentially comparable effect to the conventional treatment.
Conclusion:
PKS and JTS were found to be effective, comfortable, hygenic and acceptable in management of chronic ulcers.
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