Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

6.4K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
6.4K
Brain Imaging01:14

Brain Imaging

300
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
300

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A quantitative method to find the maximum level of spinal cord compression in degenerative cervical myelopathy.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same author

Systematic review protocol for complications following surgical decompression of degenerative cervical myelopathy.

PloS one·2024
Same author

Evaluating tissue injury in cervical spondylotic myelopathy with spinal cord MRI: a systematic review.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·2023
Same author

Beyond the aging spine - a systematic review of functional changes in the human brain in cervical spondylotic myelopathy.

GeroScience·2023
Same author

Utility of MRI in Quantifying Tissue Injury in Cervical Spondylotic Myelopathy.

Journal of clinical medicine·2023
Same author

Nonlinear Bayesian estimation of BOLD signal under non-Gaussian noise.

Computational and mathematical methods in medicine·2015

Related Experiment Video

Updated: Sep 3, 2025

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms
08:36

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms

Published on: March 21, 2019

7.3K

Transient brain-wide coactivations and structured transitions revealed in hemodynamic imaging data.

Ali Fahim Khan1, Fan Zhang1, Guofa Shou1

  • 1Stephenson School of Biomedical Engineering, University of Oklahoma, 110 W. Boyd St. DEH room 150, Norman, OK 73019, USA.

Neuroimage
|July 22, 2022
PubMed
Summary

Researchers used novel diffuse optical tomography (DOT) to identify six recurring brain states, or coactivation patterns (CAPs), in resting human brains. These transient neuronal events and their transitions reveal global brain activity dynamics.

Keywords:
Brain-wide patternsCoactivation patternsDiffuse optical tomographyFunctional connectivityGlobal activityTransition

More Related Videos

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging
17:06

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Published on: November 8, 2012

26.4K
Author Spotlight: Unlocking New Insights in fNIRS Studies - A Novel Framework for Inter-Brain Synchrony Analysis
05:59

Author Spotlight: Unlocking New Insights in fNIRS Studies - A Novel Framework for Inter-Brain Synchrony Analysis

Published on: October 6, 2023

2.7K

Related Experiment Videos

Last Updated: Sep 3, 2025

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms
08:36

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms

Published on: March 21, 2019

7.3K
Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging
17:06

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Published on: November 8, 2012

26.4K
Author Spotlight: Unlocking New Insights in fNIRS Studies - A Novel Framework for Inter-Brain Synchrony Analysis
05:59

Author Spotlight: Unlocking New Insights in fNIRS Studies - A Novel Framework for Inter-Brain Synchrony Analysis

Published on: October 6, 2023

2.7K

Area of Science:

  • Neuroimaging
  • Systems Neuroscience
  • Physiological Measurement

Background:

  • Resting-state functional connectivity (FC) and brain states are key research areas in neuroimaging.
  • Previous studies often use windowed timeframes and correlation-based methods to analyze FC.
  • Hemodynamic signals are increasingly recognized for their relevance to neuronal activity.

Purpose of the Study:

  • To investigate recurring transient brain-wide patterns in spontaneous hemodynamic fluctuations using high-density diffuse optical tomography (DOT).
  • To analyze these patterns at the resolution of single timeframes in healthy adults at rest.
  • To explore the spatiotemporal dynamics and transitions of these identified brain states.

Main Methods:

  • Utilized novel whole-head cap-based high-density diffuse optical tomography (DOT).
  • Applied data-driven analysis methods to hemodynamic signal data from thirteen healthy adults.
  • Investigated spontaneous fluctuations at single-timeframe resolution to identify coactivation patterns (CAPs).

Main Results:

  • Identified six distinct brain-wide coactivation patterns (CAPs) representing recurring brain states.
  • Observed hemispheric symmetry and highly anticorrelated pairs within CAPs.
  • Found structured transitions among CAPs, with two anterior-posterior patterns mediating state changes.
  • Elucidated global positive and negative patterns reflecting cortical co- and deactivations.
  • Demonstrated CAPs' role in generating peaks and troughs in global signals (GS).

Conclusions:

  • Transient neuronal events (CAPs), global brain activity, and structured transitions coexist and are interconnected in the human brain.
  • Findings extend observations of similar neuronal events in animal hemodynamic data.
  • Future research should explore quantitative relationships between CAPs, windowed FC, and clinical conditions with larger sample sizes.