Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Aneurysm III: Interprofessional Care

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...

Aneurysm I: Introduction

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

MAD-MT Score: A Tool to Optimize Patient Selection for Mechanical Thrombectomy in Distal Vessel Occlusions.

Stroke·2026

Same author

Standardizing Global Pediatric Stroke Pathways: Insights From a Global Survey Conducted by the Society of Neurointerventional Surgery Pediatric Special Interest Group.

Stroke (Hoboken, N.J.)·2026

Same author

Final Infarct Volume as a Surrogate End Point in Anterior Circulation ICAS-LVO Stroke: Post Hoc Secondary Analysis of RESCUE-ICAS.

Stroke (Hoboken, N.J.)·2026

Same author

Thrombectomy in Posterior Circulation Tandem Occlusions: Multicenter Comparative Analysis of Procedural Techniques and Predictors of Clinical Outcomes.

Radiology·2026

Same author

Clinical evidence standards for high-risk endovascular devices in ischemic stroke: a European multisociety consensus.

Journal of neurointerventional surgery·2026

Same author

Comparing Efficacy and Safety of Various Monoclonal Antibodies in Myasthenia Gravis: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials.

Brain and behavior·2026

Search research articles

Related Experiment Video

Updated: Sep 3, 2025

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment

Published on: September 25, 2009

Intrasaccular flow disruption for ruptured aneurysms: an international multicenter study.

Jose Danilo Bengzon Diestro¹, Mahmoud Dibas², Nimer Adeeb³

¹Department of Medical Imaging, Division of Diagnostic and Therapeutic Neuroradiology, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada danni.diestro@gmail.com.

Journal of Neurointerventional Surgery

|July 22, 2022

Summary

The Woven EndoBridge (WEB) device effectively treats both ruptured and unruptured brain aneurysms, showing similar occlusion rates and complication profiles. This study supports the WEB device

Keywords:

More Related Videos

Using a Cell-Tracer Injection to Investigate the Origin of Neointima-Forming Cells in a Rat Saccular Side Wall Model

Using a Cell-Tracer Injection to Investigate the Origin of Neointima-Forming Cells in a Rat Saccular Side Wall Model

Published on: March 16, 2022

In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging

In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging

Published on: February 25, 2022

Related Experiment Videos

Last Updated: Sep 3, 2025

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment

Published on: September 25, 2009

Using a Cell-Tracer Injection to Investigate the Origin of Neointima-Forming Cells in a Rat Saccular Side Wall Model

Using a Cell-Tracer Injection to Investigate the Origin of Neointima-Forming Cells in a Rat Saccular Side Wall Model

Published on: March 16, 2022

In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging

In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging

Published on: February 25, 2022

Area of Science:

Neurosurgery
Interventional Neuroradiology
Medical Devices

Background:

The Woven EndoBridge (WEB) device is a novel intrasaccular flow disruptor designed for treating bifurcation aneurysms.
Intracranial aneurysms pose significant risks, and treatment strategies are continuously evolving.

Purpose of the Study:

To evaluate the efficacy and safety of the WEB device in treating ruptured versus unruptured intracranial aneurysms.
To compare aneurysm occlusion rates and complication profiles between ruptured and unruptured aneurysms treated with the WEB device.

Main Methods:

A multicenter international cohort study included 676 patients with 691 aneurysms treated with the WEB device.
Aneurysms were stratified into ruptured and unruptured groups.
Propensity score matching (PSM) was employed to control for baseline characteristics.

Main Results:

No significant difference in adequate aneurysm occlusion rates at last follow-up was observed between ruptured (84.3%) and unruptured (85.8%) aneurysms in the unmatched cohort, and (94.4% vs 83.3%) in the matched cohort.
Ischemic and hemorrhagic complication rates were similar between the ruptured and unruptured groups.
No aneurysm rebleeding was documented post-WEB device implantation.

Conclusions:

The Woven EndoBridge (WEB) device demonstrates comparable radiologic outcomes and complication rates for both ruptured and unruptured intracranial aneurysms.
Treatment of ruptured aneurysms with the WEB device is feasible and effective.