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Factors Affecting Domiciliary Non-Invasive Ventilation Compliance

Amar J Shah1,2, Katia Florman1, Nitika Kaushal1

  • 1Royal Free Hospital NHS Foundation Trust, Respiratory Medicine, Pond Street, London, NW3 2QG, UK.

Lung
|July 24, 2022
PubMed

Insights

Younger patients and those with schizophrenia show lower domiciliary non-invasive ventilation (D-NIV) compliance. However, consistent use of D-NIV over a year may improve patient adherence and ventilation effectiveness.

Area of Science:

  • Respiratory Medicine
  • Clinical Ventilation
  • Patient Adherence

Background:

  • Domiciliary non-invasive ventilation (D-NIV) is crucial for managing respiratory conditions.
  • International studies on D-NIV compliance factors are limited, with scarce UK-specific data.
  • Understanding compliance is key to optimizing treatment outcomes.

Purpose of the Study:

  • To assess D-NIV compliance rates in a UK population.
  • To identify factors associated with D-NIV compliance.
  • To evaluate changes in D-NIV usage over time.

Main Methods:

  • Retrospective study of 359 patients initiated on D-NIV over 5 years.
  • Compliance defined as ≥4 hours/night for ≥70% of nights.
  • Data collected at 0-1, 3-4, and 11-12 months post-initiation.

Main Results:

  • Younger patients (median age 64 vs. 67) and those with schizophrenia (5% vs. 1-2%) exhibited lower compliance.
  • Patients with hypertension, diabetes, and heart failure showed significantly increased D-NIV usage over time.
  • D-NIV usage increased from 0-1 month to 11-12 months across all measured time points.

Conclusions:

  • Younger age and schizophrenia are associated with reduced D-NIV compliance.
  • Comorbidities like hypertension, diabetes, and heart failure may correlate with improved D-NIV use over time.
  • Persistence with D-NIV therapy over one year appears to enhance overall patient usage.

Keywords:
ComplianceNon-invasive ventilationSchizophrenia

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