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Updated: Sep 3, 2025

Corneal Donor Tissue Preparation for Endothelial Keratoplasty
Published on: June 12, 2012
Live Donation of Corneal Tissue in the Setting of Orbital Exenteration for Malignancy
Fereshteh Azad1,2, Jonathan Schiff3, Rachel Macias4
1Kresge Eye Institute, MI.
Abstract:
Background. The availability of corneal tissue is a major limiting factor in utilizing keratoplasty for correction of corneal blindness. Viable corneal tissue is typically difficult to obtain as posthumous donation is required to avoid significant morbidity and loss of vision in live patients. As a result, the possibility of obtaining viable corneal tissue from a living donor is rarely discussed. This report describes a case in which corneal donation was completed in a living patient undergoing exenteration for invasive squamous cell carcinoma of the maxillary sinus. Performing corneal donation in similar patients in the future should be considered by head and neck surgeons as an opportunity to increase the availability of corneal tissue.

