[Clinically detectable oculomotor disorders in multiple sclerosis. Results of studies on 100 patients]

The eye movements of 100 patients with a definite diagnosis of multiple sclerosis were systematically examined using simple clinical tests, whose reliability had been first verified on 40 healthy controls. In 76 of the patients one or more eye movement disorders were observed. The most frequent finding was dissociation of the horizontal saccades due to mainly abortive forms of Internuclear Ophthalmoplegia (INO). In about half of these cases other signs of INO were present. The majority of the remaining pathological findings could be attributed to cerebellar disorders which mainly consisted of saccadic hypermetria, disordered VOR-suppression or rebound nystagmus.