Electrochemical hydroboration of carbonyl compounds
Zewei Chen1, Kang Lv1, Taoyue Yuan2
1College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China. yww0715@hotmail.com.
Abstract:
A green and sustainable electrochemical hydroboration of carbonyl compounds with HBpin has been reported for the first time. Under catalyst-free and additive-free mild reaction conditions the corresponding boronic esters were obtained in excellent yields via the simple electrochemical hydroboration of various aldehydes and ketones with HBpin at room temperature. The scale-up reaction demonstrated potential practical applications. A plausible reaction mechanism was proposed based on the corresponding deuterium-labelling, radical inhibition and cyclic voltammetry experiments.
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