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BioADAPT-MRC: adversarial learning-based domain adaptation improves biomedical machine reading comprehension task.

Maria Mahbub1,2, Sudarshan Srinivasan2, Edmon Begoli2

  • 1Department of Electrical Engineering and Computer Science, University of Tennessee, Knoxville, TN 37996, USA.

Bioinformatics (Oxford, England)
|July 25, 2022
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Summary
This summary is machine-generated.

This study introduces BioADAPT-MRC, an adversarial learning framework for biomedical machine reading comprehension. BioADAPT-MRC achieves state-of-the-art results without requiring biomedical-specific labeled data.

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Area of Science:

  • Biomedical informatics
  • Natural Language Processing
  • Machine Learning

Background:

  • Biomedical machine reading comprehension (biomedical-MRC) systems require large, human-annotated datasets for high performance.
  • Domain knowledge requirement for biomedical data leads to scarcity of labeled data.
  • Direct transfer learning from general domains to biomedical domains is hindered by distribution discrepancies.

Purpose of the Study:

  • To develop a domain adaptation framework for biomedical-MRC.
  • To address the marginal distribution discrepancies between general and biomedical datasets.
  • To improve the performance of biomedical-MRC models without relying on biomedical-specific labeled data.

Main Methods:

  • An adversarial learning-based domain adaptation framework, BioADAPT-MRC, was developed.
  • The framework utilizes neural networks to bridge the distribution gap between domains.
  • It relaxes the need for pseudo-label generation for training.

Main Results:

  • BioADAPT-MRC achieved state-of-the-art performance on benchmark biomedical-MRC datasets (BioASQ-7b, 8b, 9b).
  • The framework demonstrated effectiveness without using any synthetic or human-annotated biomedical data.
  • Performance was evaluated against existing state-of-the-art methods.

Conclusions:

  • BioADAPT-MRC effectively adapts general domain models to the biomedical domain for MRC tasks.
  • The framework offers a viable solution for overcoming data scarcity in biomedical NLP.
  • Open-source availability facilitates further research and application.