Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

3.0K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
3.0K
Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

5.0K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
5.0K
The Thyroid Gland01:23

The Thyroid Gland

4.2K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
4.2K
Major Hormones and Their Functions01:27

Major Hormones and Their Functions

663
Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
663
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

20
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
20
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

14
Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
14

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of the effectiveness of digital health interventions in the postoperative management of lung transplant recipients.

Journal of cardiothoracic surgery·2026
Same author

Immunotherapy rechallenge after progression in non-small cell lung cancer: A systematic review and network meta-analysis.

iScience·2026
Same author

Sm<sup>3+</sup> Doping Enables Ultrahigh Piezoelectricity and Electrooptic Activity in PMN-PT Single Crystals.

ACS applied materials & interfaces·2026
Same author

Integrative analysis of plastome, single-copy nuclear gene <i>Pgk1</i> and SLAF-seq data uncovers multiple-origin and introgression history in polyploid <i>Agropyron cristatum</i>.

Plant diversity·2026
Same author

S100A10 promotes glycolysis and malignant progression of CCA by activating the HK2/ERK signaling pathway.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·2026
Same author

Comparative efficacy and safety of different posterior surgical approaches for Intra-articular distal humerus fractures.

Journal of orthopaedic surgery and research·2026

Related Experiment Video

Updated: Sep 3, 2025

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
04:39

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Published on: March 17, 2023

1.8K

Thyroid function changes and COVID-19 severity: egg or chicken?

Wenjie Chen1,2, Jianyong Lei3, Zhihui Li4,4

  • 1Thyroid Surgery Center, West China Hospital of Sichuan University, Chengdu, 610041, China.

Endocrine
|July 25, 2022
PubMed
Summary
This summary is machine-generated.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can alter thyroid function, with changes correlating to COVID-19 severity. However, evidence does not support thyroid dysfunction worsening COVID-19 progression.

Keywords:
COVID-19InteractionSARS-CoV-2Thyroid function change

More Related Videos

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
06:46

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

Published on: July 5, 2022

2.9K
Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
05:41

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis

Published on: February 9, 2024

723

Related Experiment Videos

Last Updated: Sep 3, 2025

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
04:39

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Published on: March 17, 2023

1.8K
A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
06:46

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

Published on: July 5, 2022

2.9K
Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
05:41

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis

Published on: February 9, 2024

723

Area of Science:

  • Endocrinology
  • Infectious Diseases
  • Virology

Background:

  • COVID-19, caused by SARS-CoV-2, presents with diverse symptoms, including potential multiorgan dysfunction.
  • Thyroid dysfunction is frequently observed in COVID-19 patients, but reported findings are often contradictory.
  • Understanding the relationship between COVID-19 and thyroid function is crucial for patient management.

Purpose of the Study:

  • To investigate the impact of SARS-CoV-2 infection on thyroid function.
  • To determine the correlation between COVID-19 severity and observed thyroid function alterations.
  • To assess whether thyroid dysfunction influences COVID-19 clinical deterioration.

Main Methods:

  • Review and analysis of existing data on COVID-19 patients with documented thyroid function tests.
  • Correlation analysis between COVID-19 severity indicators and thyroid hormone levels.
  • Evaluation of current evidence regarding the causal link between thyroid changes and disease progression.

Main Results:

  • SARS-CoV-2 infection is associated with alterations in thyroid function.
  • The extent of thyroid function changes positively correlates with the severity of COVID-19.
  • Multiple potential mechanisms underlie these thyroid function changes.
  • Current evidence is insufficient to establish that thyroid dysfunction exacerbates COVID-19.

Conclusions:

  • COVID-19 can lead to thyroid function abnormalities, the severity of which mirrors the patient's overall condition.
  • While SARS-CoV-2 impacts thyroid function, thyroid dysfunction does not appear to drive COVID-19 worsening.
  • Further research is needed to fully elucidate the complex interplay between viral infections and endocrine systems.