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Exposing the Two Contrasting Faces of STAT2 in Inflammation

Philip Duodu1, Geohaira Sosa1, Jorge Canar1

  • 1Department of Medical Genetics and Molecular Biochemistry, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.

Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research
|July 25, 2022
PubMed
Summary

Signal transducer and activator of transcription 2 (STAT2) plays a dual role in immunity. While protective against infections, dysregulated STAT2 can drive chronic inflammation and disease.

Keywords:
STAT2asthmabacterialcancerinflammationinterferonviral

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