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Related Experiment Video

Updated: Sep 3, 2025

Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability
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Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability

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Single-Level Total Disc Replacement: Mid- to Long-Term Outcomes.

Matthew Scott-Young1,2, Laurence McEntee2,3, Evelyne Rathbone2

  • 1Gold Coast Spine, Gold Coast, Australia swalter@goldcoastspine.com.au.

International Journal of Spine Surgery
|July 25, 2022
PubMed
Summary
This summary is machine-generated.

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Effects of Obesity on Minimally Invasive Lumbar Spine Surgery: A Systematic Review and Meta-Analysis.

International journal of spine surgery·2026

Total disc replacement (TDR) offers significant, sustained improvements in pain and function for lumbar degenerative disc disease (DDD). Most patients report excellent satisfaction with this treatment, even long-term.

Area of Science:

  • Spinal surgery
  • Orthopedics
  • Biomedical engineering

Background:

  • Total disc replacement (TDR) is effective for select lumbar degenerative disc disease (DDD) patients.
  • Previous studies show high patient satisfaction but often lack long-term follow-up or large cohorts.

Purpose of the Study:

  • To report mid- to long-term patient-reported outcome measures (PROMs) after single-level lumbar TDR for symptomatic DDD.

Main Methods:

  • Prospective data collection for single-level TDR via anterior approach.
  • Preoperative and serial postoperative PROMs (satisfaction, VAS, ODI, RMDQ) at 3, 6, 12 months, then annually.
  • Minimum 4-year follow-up for 211 patients (L5-S1, L4-L5 levels).

Main Results:

Keywords:
back paindegenerative disc diseaselong-term outcomeslumbar spinemotion preservationsingle leveltotal disc arthroplastytotal disc replacement

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  • Improvements in pain and function were statistically and clinically significant, maintained up to 10 years.
  • 92% of patients reported good or excellent satisfaction at final review.
  • Operative levels were L5-S1 (75.8%) and L4-L5 (24.2%).

    • Conclusions:

    • Single-level lumbar TDR provides clinically significant, sustained improvements in pain and function for selected DDD patients.
    • The procedure yields good to excellent patient satisfaction in the majority of cases.
    • Further research is needed to define long-term outcomes and survivorship.