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Updated: Sep 3, 2025

Generation of Human Alloantigen-specific T Cells from Peripheral Blood
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Peripheral Helper T Cell Responses in Human Diseases.

Hiroyuki Yoshitomi1

  • 1Department of Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Frontiers in Immunology
|July 26, 2022
PubMed
Summary

Peripheral helper T (Tph) cells are crucial in rheumatoid arthritis and other diseases. These cells aid B cells and may drive inflammation through CXCL13 production and tertiary lymphoid structure formation.

Keywords:
B cellautoimmune diseaseperipheral helper T cell (Tph)peripheral immune responsesomatic hypermutation

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