Related Experiment Video

Updated: Sep 3, 2025

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
08:05

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia

Published on: December 19, 2020

14.3K

Pulmonary Artery Enlargement: An Independent Risk Factor for Mortality in Patients Hospitalized With COVID-19

Moussa A Riachy1, Anis Ismail2, Mohamad Awali3

  • 1Division of Pulmonary and critical care medicine, Hôtel Dieu de France Hospital, Beirut, Lebanon.

Mayo Clinic Proceedings. Innovations, Quality & Outcomes
|July 26, 2022
PubMed

Insights

Baseline pulmonary artery diameter measured on CT scans can predict severe COVID-19 outcomes. Larger diameters are linked to longer hospital stays, ICU admission, and increased mortality risk in coronavirus disease 2019 patients.

Area of Science:

  • Radiology
  • Pulmonology
  • Infectious Diseases

Background:

  • Coronavirus disease 2019 (COVID-19) poses significant global health challenges.
  • Predictive markers for severe COVID-19 outcomes are crucial for patient management.
  • Pulmonary artery diameter (PAD) is a measurable parameter on computed tomography (CT) scans.

Purpose of the Study:

  • To determine if baseline pulmonary artery diameter (PAD), assessed via noncontrast nongated computed tomography (NCCT), is associated with COVID-19 outcomes.
  • To evaluate PAD as a potential prognostic indicator in hospitalized COVID-19 patients.

Main Methods:

  • Retrospective study of 465 hospitalized COVID-19 patients.
  • Measurement of baseline pulmonary artery diameter (PAD) from NCCT scans.
  • Assessment of outcomes including length of stay, ICU admission, mechanical ventilation, mortality, and functional status.

Main Results:

  • Higher baseline PAD was observed in critically ill patients requiring ICU admission and mechanical ventilation.
  • PAD correlated significantly with hospital length of stay, discharge status, and 2-month functional status.
  • A baseline PAD of ≥24.5 mm independently predicted in-hospital all-cause mortality in COVID-19 patients (OR, 2.07).

Conclusions:

  • Baseline PAD measured by NCCT is a valuable prognostic parameter for COVID-19.
  • Early identification of severe cases can be facilitated by PAD measurement.
  • PAD assessment can aid in adapting the initial management strategies for hospitalized COVID-19 patients.
Abstract

Keywords:
COVID-19, coronavirus diseaseNCCT, noncontrast nongated computed tomographyNEWS2, National Early Warning Score 2PAD, pulmonary artery diameterPCFS, Post–COVID-19 Functional StatusSARS-Cov-2, severe acute respiratory syndrome coronavirus 2

More Related Videos

The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats07:29

The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats

Published on: March 8, 2019

10.9K
Increasing Pulmonary Artery Pulsatile Flow Improves Hypoxic Pulmonary Hypertension in Piglets08:08

Increasing Pulmonary Artery Pulsatile Flow Improves Hypoxic Pulmonary Hypertension in Piglets

Published on: May 11, 2015

14.3K

Related Concept Videos

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
2.9K
Factors Affecting Pulmonary Ventilation01:19

Factors Affecting Pulmonary Ventilation

Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
1.6K
Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
42
Pulmonary Hypertension: Classification and Pathogenesis01:30

Pulmonary Hypertension: Classification and Pathogenesis

Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...
277
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
315
Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure01:16

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure

Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
315