Paracetamol analysis: evaluation of a new kit for enzymatic assay

Paracetamol in serum was assayed by a new enzymatic method, and the results compared with a high performance liquid chromatographic method. Results by the two procedures agreed well (t = 0.05). The correlation coefficient was 0.999, and the slope and intercept by Deming analysis were 0.975 and 0.003 mmol/l respectively. The enzymatic method represents a simple, accurate, precise and not too costly method with several advantages over many currently used techniques. It is eminently suitable for the smaller laboratory, and for use out of normal hours.