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Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...

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Related Experiment Video

Updated: Sep 3, 2025

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction

Published on: March 24, 2023

[Target-territory resection techniques for malignant tumors].

R Liu¹, Y Wang¹

¹Department of Hepato-pancreato-biliary Surgery, the First Medical Center of Chinese People's Liberation Army (PLA) General Hospital, Beijing 100853, China.

Zhonghua Zhong Liu Za Zhi [Chinese Journal of Oncology]

|July 26, 2022

Summary

This review introduces "target-territory resection," a novel surgical approach for solid malignant tumors. This method standardizes surgery by defining resection areas, optimizing timing, and aiming for complete tumor removal to improve patient outcomes.

Keywords:

Fourstandard surgery Malignant tumor Surgical resection Target-territory resection

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Last Updated: Sep 3, 2025

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction

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Published on: March 24, 2023

Implementation of Minimally Invasive Brain Tumor Resection in Rodents for High Viability Tissue Collection

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A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing Neoadjuvant Therapies

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing Neoadjuvant Therapies

Published on: July 28, 2020

Area of Science:

Surgical Oncology
Cancer Therapeutics
Clinical Innovation

Background:

Malignant tumors present a significant challenge due to poor prognoses.
Current treatments include surgery, radiotherapy, chemotherapy, immunotherapy, and targeted therapies.
Surgical resection remains a primary treatment for solid malignant tumors.

Purpose of the Study:

To propose and define a new surgical concept: "target-territory resection."
To standardize the implementation of surgical resection for malignant tumors.
To improve surgical outcomes by optimizing operation timing and resection range.

Main Methods:

Summarizing extensive clinical experience in malignant tumor surgery.
Defining the "target-territory" based on principles of differentiation, dynamics, and intelligence.
Integrating the concept with "four-standard surgery" principles.

Main Results:

Introduction of a standardized framework for malignant tumor surgery.
Method for determining optimal surgical timing and resection scope.
Potential for achieving zero tumor burden post-resection.

Conclusions:

"Target-territory resection" offers a standardized and optimized approach to surgical treatment of solid malignant tumors.
This novel concept aims to enhance surgical precision and efficacy.
The goal is to achieve complete tumor removal and improve patient prognosis.