Treatment horizon in multiple myeloma
Cinnie Yentia Soekojo1,2,3, Wee Joo Chng1,2,3
1Department of Hematology-Oncology, National University Cancer Institute, Singapore, National University Health System, Singapore, Singapore.
Objectives:
This paper reviews current and emerging therapies for multiple myeloma (MM).
Methods:
Narrative review.
Results:
MM is a complex, heterogenous condition, and in recent years there has been an expansion in the number and range of treatments. Several new treatment approaches, including enhanced monoclonal antibodies, antibody-drug conjugates, bispecific T-cell engagers, and chimeric antigen-T-cell therapy are under development.
Conclusions:
The emergence of new treatments that aim to tackle MM-associated immune dysfunction has led to improvements in overall survival.
More Related Videos
09:41An Organotypic High Throughput System for Characterization of Drug Sensitivity of Primary Multiple Myeloma Cells
Published on: July 15, 2015
10:04Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis
Published on: May 1, 2015
Related Concept Videos
Treatment Resistant Cancers
Targeted Cancer Therapies
There are several types of targeted therapies against...
Combination Therapies and Personalized Medicine
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
