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Updated: Sep 3, 2025
14:52
Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication
Published on: December 11, 2013
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Peripheral arterial disease and hypertension.
Aashish Gupta1, Rajan A G Patel
1Ochsner Medical Center, New Orleans, Louisiana, USA.
Current Opinion in Cardiology
|July 26, 2022
Summary
Blood pressure management in peripheral arterial disease (PAD) is challenging due to conflicting evidence on optimal targets. Further research is needed to guide treatment for hypertension in PAD patients.
Area of Science:
- Cardiovascular Medicine
- Vascular Biology
- Hypertension Research
Background:
- Hypertension (HTN) is a significant risk factor for atherosclerosis and peripheral arterial disease (PAD).
- PAD impacts over 250 million individuals globally, correlating with poorer clinical outcomes.
- Current blood pressure management in PAD patients is suboptimal despite numerous studies.
Purpose of the Study:
- To review the current state of blood pressure management in patients with PAD.
- To highlight the conflicting evidence regarding optimal blood pressure targets in PAD.
- To identify the need for further research in antihypertensive treatment for PAD.
Main Methods:
- Review of existing literature and clinical guidelines on hypertension in PAD.
- Analysis of recent studies investigating blood pressure goals in PAD patients.
- Evaluation of antihypertensive drug class efficacy in the PAD population.
Main Results:
- Conflicting evidence exists on ideal blood pressure goals for PAD, with some studies indicating adverse effects from overly low targets.
- Current clinical guidelines recommend similar blood pressure targets for PAD patients as for those without PAD.
- No specific antihypertensive drug class has demonstrated a definitive advantage in PAD patients.
Conclusions:
- Optimal blood pressure targets for PAD patients remain uncertain.
- Prospective randomized trials are essential to determine the best blood pressure targets.
- Further research is required to differentiate the effectiveness of various antihypertensive drugs in reducing adverse outcomes in PAD.
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