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Updated: Sep 3, 2025

Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides
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Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides

Published on: May 26, 2019

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The Bifunctional Silyl Reagent Me2 (CH2 Cl)SiCF3 Enables Highly Enantioselective Ketone Trifluoromethylation and

Bo-Shuai Mu1, Yang Gao1, Fu-Ming Yang1

  • 1Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal University, 3663N Zhongshan Road, Shanghai, 200062, China.

Angewandte Chemie (International Ed. in English)
|July 26, 2022
PubMed

Keywords:
Asymmetric SynthesisFluorineTandem SynthesisTertiary AlcoholsTrifluoromethylation

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