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[Systemic toxicity secondary to local anesthetic infiltration]
R López-Ruiz1, J D Guerra-Hiraldo1, J Dotor-García Soto1
1Hospital Universitario Virgen Macarena, 41003 Sevilla, España.
Revista De Neurologia
|July 26, 2022
Summary
Local anaesthetics (LA) can cause systemic toxicity, presenting with neurological symptoms. Early recognition of these signs is crucial for managing potentially fatal haemodynamic events and improving patient outcomes.
Area of Science:
- Anesthesiology
- Pharmacology
Background:
- Local anesthetics (LA) offer a favorable risk/benefit profile compared to general anesthetics.
- Despite their widespread use, local anesthetics can cause adverse effects.
Observation:
- A case report details a 44-year-old man experiencing systemic toxicity from intrathecal bupivacaine.
- This toxicity occurred following hip arthroplasty surgery.
Findings:
- Systemic toxicity from local anesthetics can manifest as neurological symptoms.
- Neurological symptoms may precede or occur with hemodynamic instability.
Implications:
- Early identification of neurological symptoms is vital for predicting and managing life-threatening hemodynamic events.
- Awareness of local anesthetic toxicity and its clinical management is essential for improving patient prognosis.
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