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Updated: Sep 3, 2025

Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness
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Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness

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Arterial stiffness and nocturnal hypertension in preterm children and adolescents

Athanasia Chainoglou1, Kosmas Sarafidis2, Katerina Chrysaidou1

  • 11st Department of Pediatrics, School of Medicine, Faculty of Health Sciences Aristotle University of Thessaloniki, Hippokratio Hospital, Thessaloniki, Greece.

Journal of Hypertension
|July 26, 2022
PubMed

Insights

Children born preterm face higher risks for nocturnal hypertension and arterial stiffness. Early detection of high blood pressure and obesity prevention are crucial for long-term cardiovascular health in these individuals.

Area of Science:

  • Pediatric Cardiology
  • Vascular Biology
  • Public Health

Background:

  • Preterm birth is linked to chronic diseases like hypertension in later life.
  • Understanding early cardiovascular changes in preterm individuals is vital.

Purpose of the Study:

  • To investigate the association of preterm birth with blood pressure and arterial stiffness in children and adolescents.

Main Methods:

  • A prospective case-control study involving 52 preterm and 26 full-term children.
  • Ambulatory blood pressure monitoring (ABPM) and carotid-femoral pulse wave velocity (PWV) assessment were performed.

Main Results:

  • Preterm children showed higher nocturnal systolic blood pressure (SBP) z scores.
  • Arterial stiffness (PWV z score) was significantly higher in preterm individuals.
  • Nocturnal hypertension was prevalent in 78% of ex-preterm children with ambulatory hypertension.

Conclusions:

  • Preterm birth is associated with elevated nocturnal blood pressure and increased arterial stiffness during childhood and adolescence.
  • Early hypertension detection and obesity prevention are recommended to mitigate future cardiovascular risks in preterm individuals.
Abstract

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