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Benign Meningioma With Rare Radiological and Behavioral Features
Donghui Wen1, Dan Xu2, Lu Wang3
1Department of Neurology, The Fourth Affiliated Hospital, Zhejiang University School of Medicine.
The Journal of Craniofacial Surgery
|July 26, 2022
Summary
This rare brain convexity meningioma mimicked a bone tumor due to significant skull osteolysis. Early detection and awareness are crucial for accurate diagnosis and treatment of this unusual central nervous system neoplasm.
Area of Science:
- Neuro-oncology
- Skeletal oncology
Background:
- Meningiomas are typically dura-based central nervous system neoplasms.
- Extremely rare meningiomas can occur at the brain convexity without dural attachment.
Observation:
- A 57-year-old woman presented with an incidental scalp lump.
- Radiology showed an osteolytic lesion in the parietal bone, initially diagnosed as a bone tumor.
- Surgery revealed a convexity tumor without dural attachment, invading the brain parenchyma and causing skull osteolysis.
Findings:
- Histological and immunohistochemical analysis confirmed a meningothelial meningioma.
- The tumor caused significant osteolysis and dural destruction despite its small size.
Implications:
- This case highlights the diagnostic challenges of convexity meningiomas, which can be mistaken for primary bone tumors.
- Clinicians must consider meningioma in the differential diagnosis of skull osteolytic lesions.
- Further research is needed to understand the mechanism of osteolysis in meningiomas.
