Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

2.5K
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
2.5K
Primary Lymphoid Organs01:16

Primary Lymphoid Organs

5.0K
Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
5.0K
Lymphoid Cells and Tissues01:18

Lymphoid Cells and Tissues

1.5K
Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
1.5K
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

639
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
639
Lymphatic Vessels and Lymph Transport01:16

Lymphatic Vessels and Lymph Transport

9.2K
Lymphatic vessels, known as lymphatics, are crucial in transporting lymph from peripheral tissues to our venous system. This process begins with lymph entering through tiny capillaries that branch through tissues. These capillaries have unique features such as larger diameters, thinner walls, and a distinctive one-way valve system formed by overlapping endothelial cells.
This one-way system allows fluids, solutes, and even pathogens to enter but prevents their return to the intercellular...
9.2K
Glaucoma: Overview01:25

Glaucoma: Overview

712
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
712

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Promise and pragmatism of AI in global-scale digital pathology: pan-cancer approaches for clinical practice.

Journal of clinical pathology·2026
Same author

GWAS meta-analysis provides new insights into uveal melanoma risk.

British journal of cancer·2026
Same author

Novel CRISPR-Cas9 BAP1 knockout pre-clinical tumor model recapitulates human melanoma tumorigenesis and immune evolution.

Communications biology·2026
Same author

Lenalidomide-rituximab or lenalidomide-rituximab-bendamustine for relapsed/refractory follicular lymphoma: primary and final analysis of the randomized phase II HOVON110/ReBeL study.

Haematologica·2026
Same author

Tissue resident memory T cells populate the human uveal tract.

Scientific reports·2026
Same author

The complement system contributes to the immunosuppressive microenvironment of uveal melanoma.

Journal of translational medicine·2026

Related Experiment Video

Updated: Sep 3, 2025

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
06:15

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

1.4K

Conjunctival Lymphoma.

Lindsay A McGrath1,2, David A Ryan3, Sunil K Warrier4

  • 1Queensland Ocular Oncology Service, Terrace Eye Centre, Brisbane, QLD, Australia. lindsay.mcg@gmail.com.

Eye (London, England)
|July 26, 2022
PubMed
Summary

Conjunctival lymphoma, often extranodal marginal zone B-cell lymphoma (EMZL), presents as painless lesions. Advances in molecular diagnostics improve prediction of recurrence and systemic disease for this ocular malignancy.

More Related Videos

Author Spotlight: Advancing VRL Diagnosis Using Cell-Free DNA Extraction from Vitreous Humor
06:20

Author Spotlight: Advancing VRL Diagnosis Using Cell-Free DNA Extraction from Vitreous Humor

Published on: January 12, 2024

2.1K
A Rabbit Model of Aqueous-Deficient Dry Eye Disease Induced by Concanavalin A Injection into the Lacrimal Glands: Application to Drug Efficacy Studies
08:04

A Rabbit Model of Aqueous-Deficient Dry Eye Disease Induced by Concanavalin A Injection into the Lacrimal Glands: Application to Drug Efficacy Studies

Published on: January 24, 2020

12.5K

Related Experiment Videos

Last Updated: Sep 3, 2025

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
06:15

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

1.4K
Author Spotlight: Advancing VRL Diagnosis Using Cell-Free DNA Extraction from Vitreous Humor
06:20

Author Spotlight: Advancing VRL Diagnosis Using Cell-Free DNA Extraction from Vitreous Humor

Published on: January 12, 2024

2.1K
A Rabbit Model of Aqueous-Deficient Dry Eye Disease Induced by Concanavalin A Injection into the Lacrimal Glands: Application to Drug Efficacy Studies
08:04

A Rabbit Model of Aqueous-Deficient Dry Eye Disease Induced by Concanavalin A Injection into the Lacrimal Glands: Application to Drug Efficacy Studies

Published on: January 24, 2020

12.5K

Area of Science:

  • Ophthalmology
  • Oncology
  • Hematology

Background:

  • Conjunctival lymphoma is an ocular malignancy originating from lymphocytes.
  • Extranodal marginal zone B-cell lymphoma (EMZL) is the most common subtype, but others like DLBCL, FL, MCL, and T-cell lymphomas also occur.
  • Clinical presentation is often non-specific, characterized by painless, salmon-pink conjunctival lesions.

Purpose of the Study:

  • To review the classification, clinical features, diagnostic techniques, and management strategies for conjunctival lymphomas.
  • To highlight emerging prognostic indicators based on cytogenetic and molecular features.

Main Methods:

  • Review of existing literature on conjunctival lymphoma.
  • Analysis of clinical manifestations and diagnostic approaches.
  • Evaluation of current and emerging treatment modalities.
  • Assessment of advancements in molecular diagnostics for prognostication.

Main Results:

  • Conjunctival lymphoma encompasses various subtypes, with EMZL being predominant.
  • Standard treatments include local immunomodulation (Interferon-α2b, Rituximab) and radiation.
  • Next-generation sequencing offers improved prediction of recurrence and systemic spread.
  • Cytogenetic and molecular features are crucial for prognostication.

Conclusions:

  • Conjunctival lymphoma management is evolving with improved diagnostic and prognostic tools.
  • Personalized treatment strategies can be informed by molecular profiling.
  • Early detection and accurate prognostication are key to managing this ocular malignancy.