Related Experiment Video
Updated: Sep 3, 2025
04:33
Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
Published on: April 26, 2024
780
Association between migraine and cognitive impairment.
Lihua Gu1,2, Yanjuan Wang3, Hao Shu3
1Department of Neurology, Affiliated ZhongDa Hospital, School of Medicine, Southeast University, No. 87 Dingjiaqiao Road, Nanjing, 210009, Jiangsu, China. g714775808@126.com.
The Journal of Headache and Pain
|July 26, 2022
Summary
Migraine is linked to poorer general cognitive and language function. This meta-analysis also found that migraine increases the risk of developing dementia, highlighting the need for intervention in at-risk individuals.
Area of Science:
- Neurology
- Cognitive Science
- Epidemiology
Background:
- Inconsistent findings exist regarding the link between migraine and cognitive impairment.
- Previous research has yielded conflicting results on migraine's association with dementia risk.
Purpose of the Study:
- To conduct a meta-analysis comparing cognitive function in migraine patients versus non-migraine subjects.
- To investigate the association between migraine and the risk of dementia.
Main Methods:
- A comprehensive literature search was performed across multiple databases up to June 2022.
- Data analysis was conducted using STATA 12.0 software.
Main Results:
- Migraine patients exhibited lower general cognitive function (SMD = -0.40) and language function (SMD = -0.14).
- No significant differences were observed in visuospatial function, attention, executive function, or memory.
- A significant association was found between migraine and an increased risk of dementia (OR/RR = 1.30).
Conclusions:
- Migraine is associated with diminished general cognitive and language abilities.
- Migraine is linked to a higher risk of all-cause dementia, vascular dementia (VaD), and Alzheimer's disease (AD).
- Neurologists should proactively manage migraineurs with cognitive impairment risk factors to prevent cognitive decline.
Related Concept Videos
01:27Language and Cognition
427
Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.
427
01:30Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists
199
Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
199
01:14Role of Cerebellum and Prefrontal Cortex in Memory
567
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
567
01:30Cognitive Development During Adulthood
237
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
237
01:30Negative and Cognitive Symptoms of Schizophrenia
116
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
116