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Preliminary Evidence on Pulmonary Function after Asymptomatic and Mild COVID-19 in Children

Costanza Di Chiara1, Silvia Carraro2, Stefania Zanconato2

  • 1Division of Pediatric Infectious Diseases, Department of Women's and Children's Health, University of Padua, 35128 Padua, Italy.

Children (Basel, Switzerland)
|July 27, 2022
PubMed

Insights

Children infected with the coronavirus disease 2019 (COVID-19) did not experience long-term lung problems or respiratory symptoms after mild infections. This study followed pediatric patients for up to 10 months post-infection.

Area of Science:

  • Pediatric Pulmonology
  • Infectious Diseases
  • Respiratory Medicine

Background:

  • Limited data exist on the long-term pulmonary effects of SARS-CoV-2 in children.
  • Adults can experience persistent pulmonary function decline after COVID-19, regardless of initial severity.

Purpose of the Study:

  • To evaluate the long-term pneumological impact of asymptomatic or mild SARS-CoV-2 infection in children.
  • To assess for chronic respiratory symptoms and lung function impairment in pediatric COVID-19 survivors.

Main Methods:

  • A single-center, prospective, observational study was conducted.
  • 61 children aged 6-18 years with a history of asymptomatic/mild COVID-19 were included.
  • Pulmonary function was assessed using spirometry approximately 10 months post-infection.

Main Results:

  • No children reported respiratory symptoms at follow-up.
  • No participants required inhaled respiratory therapies.
  • All children demonstrated normal lung function on spirometry.

Conclusions:

  • Asymptomatic or mild SARS-CoV-2 infection in children and adolescents does not appear to lead to chronic respiratory symptoms.
  • Pediatric patients in this cohort did not exhibit lung function impairment following mild COVID-19.
  • The long-term respiratory outlook for children with mild COVID-19 appears favorable.
Abstract

Keywords:
COVID-19childrenlong-covidpulmonary functionspirometry

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