Related Experiment Video
Updated: Sep 3, 2025

Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers
Published on: July 28, 2022
Nutrition in Pediatric Intensive Care: A Narrative Review
Milan Kratochvíl1,2, Jozef Klučka1,2, Eva Klabusayová1,2
1Department of Paediatric Anaesthesiology and Intensive Care Medicine, University Hospital Brno and Faculty of Medicine, Masaryk University, Kamenice 5, 625 00 Brno, Czech Republic.
Insights
Pediatric intensive care nutrition support is crucial for critically ill children due to their higher metabolic demands. Early enteral nutrition, prioritizing protein in the acute phase, is key for recovery and rehabilitation.
Area of Science:
- Pediatric critical care medicine
- Clinical nutrition
- Metabolic support
Background:
- Critically ill children have higher metabolic demands and lower energy reserves than adults, increasing starvation vulnerability.
- Prompt initiation of nutrition support post-admission and stabilization is vital.
- Enteral nutrition is preferred over parenteral when feasible.
Purpose of the Study:
- To outline optimal nutrition support strategies for critically ill children.
- To emphasize the importance of early and appropriate nutritional interventions.
Main Methods:
- Review of current evidence and clinical guidelines for pediatric intensive care nutrition.
- Discussion of enteral nutrition routes and timing.
- Emphasis on macronutrient requirements during different illness phases.
Main Results:
- Early enteral nutrition (oral or gastric tube) is recommended if no contraindications exist.
- High protein delivery is crucial during the acute catabolic phase.
- Adequate energy provision is essential for the subsequent anabolic and rehabilitation phases.
Conclusions:
- Nutrition support is a cornerstone of pediatric intensive care.
- Tailoring nutrition strategies to the child's metabolic state and illness phase optimizes outcomes.
- Timely and appropriate nutrition management facilitates recovery and improves prognosis.
Abstract:
Nutrition support in pediatric intensive care is an integral part of a complex approach to treating critically ill children. Smaller energy reserves with higher metabolic demands (a higher basal metabolism rate) compared to adults makes children more vulnerable to starvation. The nutrition supportive therapy should be initiated immediately after intensive care admission and initial vital sign stabilization. In absence of contraindications (unresolving/decompensated shock, gut ischemia, critical gut stenosis, etc.), the preferred type of enteral nutrition is oral or via a gastric tube. In the acute phase of critical illness, due to gluconeogenesis and muscle breakdown with proteolysis, the need for high protein delivery should be emphasized. After patient condition stabilization, the acute phase with predominant catabolism converts to the anabolic phase and intensive rehabilitation, where high energy demands are the keystone of a positive outcome.
Related Concept Videos
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
Chronic Kidney Disease III: Interprofessional Care
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Acute Kidney Injury VI: Nursing Management
Acute Kidney Injury V: Interprofessional Care

