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Applications of Smartphone-Based Aptasensor for Diverse Targets Detection
Ying Lan1, Baixun He1, Cherie S Tan1,2
1Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin 300072, China.
Biosensors
|July 27, 2022
Summary
Aptasensors, which use aptamers for biomolecule detection, are effective for smartphone-based point-of-care testing. This review covers aptasensor technologies for detecting various targets like metal ions and proteins.
Area of Science:
- Biotechnology
- Biosensors
- Molecular Recognition
Background:
- Aptamers are functional ligands with high specificity and affinity for target molecules.
- Aptamers serve as recognition layers in biosensors, enabling the detection of various biomolecules.
- Aptasensors offer specific, sensitive, and cost-effective biosensing capabilities.
Purpose of the Study:
- To review smartphone-based aptasensors for diverse target detection.
- To highlight the integration of aptasensors with mobile devices for point-of-care testing (POCT).
- To discuss underlying aptasensor technologies and configurations.
Main Methods:
- Literature review of aptasensor applications.
- Focus on smartphone integration for biosensing.
- Analysis of aptasensor designs for target detection.
Main Results:
- Smartphone-based aptasensors enable rapid detection of targets including metal ions, nucleic acids, proteins, and cells.
- These devices offer advantages for immediate results in biological testing.
- Various aptasensor technologies and configurations have been developed.
Conclusions:
- Smartphone-based aptasensors represent a promising platform for accessible and efficient POCT.
- The versatility of aptamers allows for the detection of a wide range of analytes.
- Further development in aptasensor technology can enhance diagnostic capabilities.
