Related Experiment Video
Updated: Sep 3, 2025

Diagonal Method to Measure Synergy Among Any Number of Drugs
Published on: June 21, 2018
Essential Conditions for the Full Synergy of Probability of Occurrence Distributions
Rubem P Mondaini1, Simão C de Albuquerque Neto1
1COPPE, Centre of Technology, Federal University of Rio de Janeiro, Rio de Janeiro 21941-901, Brazil.
Abstract:
In this contribution, we specify the conditions for assuring the validity of the synergy of the distribution of probabilities of occurrence. We also study the subsequent restriction on the maximal extension of the strict concavity region on the parameter space of Sharma-Mittal entropy measures, which has been derived in a previous paper in this journal. The present paper is then a necessary complement to that publication. Some applications of the techniques introduced here are applied to protein domain families (Pfam databases, versions 27.0 and 35.0). The results will show evidence of their usefulness for testing the classification work performed with methods of alignment that are used by expert biologists.
Related Concept Videos
Probability in Statistics
An example of a simple event is a coin toss. The result of a coin toss is either a head or a tail. Here, head and tail are two simple events. These two simple events make up the sample space. Further, the probability of an event occurring falls within the range of 0 to 1. The probability of an...
Probability Distributions
A discrete probability distribution is a probability distribution of discrete random variables. It can be categorized into binomial probability distribution and Poisson...
Probability Laws
Determination of Expected Frequency
Unusual Results
According to the range rule of thumb, any value above or below two standard deviations, 2σ from the mean, μ is considered unusual.
Maximum unusual value =...
Hardy-Weinberg Principle

