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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

712
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
712

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An Alternative and Validated Injection Method for Accessing the Subretinal Space via a Transcleral Posterior Approach
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Choroidal Thickness Increase after Subliminal Transscleral Cyclophotocoagulation.

Florian Baltă1,2, Valentin Dinu1,2, Mihail Zemba1,3

  • 1Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.

Diagnostics (Basel, Switzerland)
|July 27, 2022
PubMed
Summary

Subliminal transscleral cyclophotocoagulation shows significant success in treating refractory glaucoma. Increased choroidal thickness correlates with reduced intraocular pressure and procedure success, potentially serving as a predictive factor.

Keywords:
choroidal thicknessintraocular pressuresubliminal transscleral cyclophotocoagulation

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Area of Science:

  • Ophthalmology
  • Glaucoma Research
  • Surgical Innovation

Background:

  • Glaucoma management often requires advanced interventions for refractory cases.
  • Subliminal transscleral cyclophotocoagulation is an emerging technique for intraocular pressure control.
  • Understanding treatment efficacy and predictive markers is crucial for patient outcomes.

Purpose of the Study:

  • To evaluate the success rate of subliminal transscleral cyclophotocoagulation in drug-refractory glaucoma.
  • To investigate the relationship between intraocular pressure reduction and choroidal thickness changes.
  • To identify potential clinical predictors for treatment success.

Main Methods:

  • A 3-year pre-post study involving 81 eyes of 67 patients with refractory glaucoma.
  • Patients underwent subliminal transscleral cyclophotocoagulation.
  • Key variables measured: intraocular pressure, best-corrected visual acuity, and choroidal thickness.

Main Results:

  • Success rates (intraocular pressure < 21 mmHg) were 80% at 1 month, decreasing to 50.6% at 1 year.
  • A strong correlation was found between decreased intraocular pressure and increased choroidal thickness at 1 year.
  • Increased choroidal thickness at 1 month correlated with the procedure's success rate.

Conclusions:

  • A statistically significant correlation exists between success rate, intraocular pressure reduction, and choroidal thickness.
  • Early increases in choroidal thickness may predict the long-term success of subliminal transscleral cyclophotocoagulation.
  • Further research is needed to confirm choroidal thickening as an indicator of enhanced uveoscleral drainage.