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COVID-19-Related Mortality amongst Physicians in Italy: Trend Pre- and Post-SARS-CoV-2 Vaccination Campaign
Alberto Modenese1, Tom Loney2, Fabriziomaria Gobba1
1Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Insights
COVID-19 vaccination campaigns significantly reduced mortality among Italian physicians. Mortality rates in March-May 2021 were 12 times lower than in March-May 2020, demonstrating vaccine effectiveness in protecting healthcare workers.
Area of Science:
- Public Health
- Epidemiology
- Infectious Diseases
Background:
- Healthcare workers faced high COVID-19 mortality globally during the SARS-CoV-2 pandemic.
- Anti-COVID-19 vaccination campaigns aimed to protect frontline workers and decrease occupational mortality.
Purpose of the Study:
- To analyze COVID-19-related mortality data for physicians in Italy.
- To compare mortality rates before and after the widespread implementation of COVID-19 vaccination.
Main Methods:
- Comparative analysis of crude COVID-19 mortality rates among Italian doctors.
- Data comparison between March-May 2020 (pre-vaccination) and March-May 2021 (high vaccination coverage).
- Correlation analysis between vaccine doses administered and mortality trends.
Main Results:
- Physician COVID-19 mortality was 12 times higher in March-May 2020 compared to March-May 2021.
- A strong inverse correlation was observed between cumulative vaccine doses and mortality.
- Recent trends (Sept-Oct 2021) suggest the need for a third vaccine dose.
Conclusions:
- The COVID-19 vaccination campaign was effective in protecting Italian physicians and reducing SARS-CoV-2-related mortality.
- Vaccine effectiveness is supported by the significant decrease in mortality post-vaccination.
- Data indicates the ongoing importance of booster doses for sustained protection.
Abstract:
Globally, there has been a high burden of COVID-19-related mortality amongst physicians and other healthcare workers during the ongoing SARS-CoV-2 pandemic. Fortunately, anti-COVID-19 vaccination campaigns have helped to protect frontline workers and reduce COVID-19-related mortality amongst this occupational group. We analyzed COVID-19-related mortality data for doctors in Italy and compared the crude mortality rate between March-May 2020 (i.e., the beginning of the pandemic in Italy, with the highest rates of COVID-19-related deaths) and the same time period in March-May 2021 (high vaccination coverage amongst Italian physicians). The mortality rate was 12 times higher in March-May 2020 compared to the same time period after the start of the Italian vaccination campaign. Moreover, there was a strong inverse correlation between the number of deaths and the cumulative number of vaccine doses administered in the Italian population. Although non-pharmaceutical interventions, virus evolution and environmental factors probably had an effect, our analysis clearly supports the hypothesis that the vaccination campaign helped to protect Italian physicians and reduce COVID-19-related mortality. The latest available death trends from September to October 2021 for both physicians and the general population are also in favor of the need for the third vaccine dose, currently underway for the majority of the population at risk.
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