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Updated: Sep 3, 2025

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
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Published on: July 11, 2013

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Metabolic Comorbidities and Cardiovascular Disease in Pediatric Psoriasis: A Narrative Review

Andrea Marani1, Giulio Rizzetto1, Giulia Radi1

  • 1Clinic of Dermatology, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, 60121 Ancona, Italy.

Healthcare (Basel, Switzerland)
|July 27, 2022
PubMed

Insights

Pediatric psoriasis patients often experience metabolic issues like obesity and insulin resistance. Early awareness and tailored treatment are crucial for managing these associated health conditions in children.

Area of Science:

  • Dermatology
  • Pediatrics
  • Metabolic Syndrome

Background:

  • Psoriasis vulgaris is a chronic inflammatory skin condition.
  • It is increasingly recognized as a systemic disease with significant comorbidities.
  • Metabolic comorbidities are particularly prevalent in children with psoriasis.

Purpose of the Study:

  • To review and synthesize current knowledge on metabolic comorbidities in pediatric psoriasis.
  • To highlight the key metabolic health issues affecting children with this condition.

Main Methods:

  • This study employed a narrative review approach.
  • It synthesized existing literature on metabolic comorbidities in psoriatic children.

Main Results:

  • Obesity is a primary metabolic comorbidity in children with psoriasis.
  • Insulin resistance and type 2 diabetes are frequently observed.
  • Cardiovascular disease and dyslipidemia are also significant concerns.

Conclusions:

  • Dermatologists must recognize and actively manage metabolic comorbidities in pediatric psoriasis patients.
  • Therapeutic strategies should be individualized based on the patient's overall clinical status.
  • Addressing metabolic health is integral to comprehensive psoriasis care in children.

Keywords:
childrencomorbiditiesdiabeteslipidslipoproteinmetabolismobesityperoxidationpsoriasis

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