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Factors Associated with Variability in Pulse Wave Transit Time Using Pulse Oximetry: A Retrospective Study
Hilmanda Budiman1, Ryo Wakita1, Takaya Ito1
1Department of Dental Anesthesiology and Orofacial Pain Management, Tokyo Medical and Dental University, Yushima, Bunkyo-ku 1-5-45, Tokyo 113-8549, Japan.
Journal of Clinical Medicine
|July 27, 2022
Summary
Pulse wave transit time (PWTT) variability is linked to local anesthesia, patient age, hypertension, and dental phobia. High epinephrine doses in local anesthesia correlate with increased PWTT variability.
Area of Science:
- Cardiology
- Anesthesiology
- Biomedical Engineering
Background:
- Pulse wave transit time (PWTT) measures blood pressure (BP) changes via vessel wall compliance.
- Factors influencing PWTT variability remain unclear, necessitating further investigation.
Purpose of the Study:
- To investigate blood pressure changes related to PWTT variations.
- To identify clinical characteristics associated with PWTT variability during dental procedures under sedation.
Main Methods:
- Collected data from 485 dental procedures under conscious sedation.
- Recorded heart rate, BP, and PWTT waves during local anesthesia (LA) administration.
- Analyzed PWTT variability, categorizing cases into large (LPV) and small (SPV) variability groups.
Main Results:
- Large PWTT variability did not reliably detect BP changes.
- LA use, patient age, hypertension, and dental phobia were associated with PWTT variability.
- Epinephrine doses exceeding 36.25 µg in LA correlated with PWTT variability >15 ms.
Conclusions:
- PWTT variability is influenced by specific clinical factors and LA composition.
- Understanding these factors is crucial for interpreting PWTT measurements in clinical settings.
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