Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Overview of Algae01:28

Overview of Algae

162
The kingdom Archaeplastida encompasses red and green algae, along with land plants. Unlike other protists with chloroplasts that arose through secondary endosymbiosis, only red and green algae originated from primary endosymbiotic events. This diverse group of eukaryotic organisms contains chlorophyll and performs oxygenic photosynthesis.Algae exist in various forms, from large brown kelp in coastal waters to green scum in puddles and stains on rocks or soil. Some species are responsible for...
162

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Predictive Algal Systems Biology: Integrating Omics, Genome-Scale Metabolic Models, and Machine Learning.

Bioengineering (Basel, Switzerland)·2026
Same author

Genome assembly and annotation of <i>Scenedesmus bijugus var. obtusiusculus</i> AT-UAM from Cuatro Ciénegas, México.

Microbiology resource announcements·2026
Same author

Natural color biofactories: advancing the spectrum of pigment production in phototrophic microbes.

FEMS microbes·2025
Same author

Mixotrophic growth of a ubiquitous marine diatom.

Science advances·2024
Same author

A model industrial workhorse: Bacillus subtilis strain 168 and its genome after a quarter of a century.

Microbial biotechnology·2023
Same author

Synthesis of glycerol carbonate from glycerin with CaCO<sub>3</sub> in a batch reactor.

Designed monomers and polymers·2022

Related Experiment Video

Updated: Sep 3, 2025

High-Throughput Metabolic Profiling for Model Refinements of Microalgae
11:07

High-Throughput Metabolic Profiling for Model Refinements of Microalgae

Published on: December 4, 2021

3.9K

Multi-Objective Optimization of Microalgae Metabolism: An Evolutive Algorithm Based on FBA.

Monica Fabiola Briones-Baez1, Luciano Aguilera-Vazquez1, Nelson Rangel-Valdez2

  • 1TECNM/Instituto Tecnológico de Ciudad Madero, División de Estudios de Posgrado e Investigación, Los Mangos 89440, Mexico.

Metabolites
|July 27, 2022
PubMed
Summary

This study introduces a novel evolutionary algorithm for multi-objective metabolic modeling in microalgae. It enhances metabolic engineering by providing more solutions for optimizing biomass and bioproducts like protein and carbohydrates.

Keywords:
FBAcell metabolismmulti-objective optimizationnsgaii

More Related Videos

Optimize Flue Gas Settings to Promote Microalgae Growth in Photobioreactors via Computer Simulations
14:33

Optimize Flue Gas Settings to Promote Microalgae Growth in Photobioreactors via Computer Simulations

Published on: October 1, 2013

14.5K
Coupling Carbon Capture from a Power Plant with Semi-automated Open Raceway Ponds for Microalgae Cultivation
08:17

Coupling Carbon Capture from a Power Plant with Semi-automated Open Raceway Ponds for Microalgae Cultivation

Published on: August 14, 2020

5.3K

Related Experiment Videos

Last Updated: Sep 3, 2025

High-Throughput Metabolic Profiling for Model Refinements of Microalgae
11:07

High-Throughput Metabolic Profiling for Model Refinements of Microalgae

Published on: December 4, 2021

3.9K
Optimize Flue Gas Settings to Promote Microalgae Growth in Photobioreactors via Computer Simulations
14:33

Optimize Flue Gas Settings to Promote Microalgae Growth in Photobioreactors via Computer Simulations

Published on: October 1, 2013

14.5K
Coupling Carbon Capture from a Power Plant with Semi-automated Open Raceway Ponds for Microalgae Cultivation
08:17

Coupling Carbon Capture from a Power Plant with Semi-automated Open Raceway Ponds for Microalgae Cultivation

Published on: August 14, 2020

5.3K

Area of Science:

  • * Metabolic modeling and systems biology
  • * Microalgae biotechnology and metabolic engineering

Background:

  • * Metabolic models are crucial for understanding microalgae metabolism and physiological states.
  • * Flux Balance Analysis (FBA) typically optimizes a single objective, limiting comprehensive analysis.
  • * Multi-objective optimization is gaining traction for simultaneous production of biomass and bioproducts.

Purpose of the Study:

  • * To propose an in silico multi-objective metabolic model using an evolutionary algorithm.
  • * To offer a broader approximation of the Pareto frontier for improved decision-making in metabolic engineering.
  • * To validate the model on *Chlamydomonas reinhardtii* for optimizing protein, carbohydrate, and CO2 uptake.

Main Methods:

  • * Development of a novel evolutionary algorithm for multi-objective metabolic modeling.
  • * Application of the algorithm to a reduced metabolic network of *Chlamydomonas reinhardtii*.
  • * Comparative analysis against a classic FBA tool for solution space exploration.

Main Results:

  • * The proposed evolutionary algorithm achieved a broader approximation of the Pareto frontier.
  • * A significantly higher number of solutions were obtained compared to the classic FBA tool.
  • * Successful optimization of protein, carbohydrate production, and CO2 uptake was demonstrated.

Conclusions:

  • * The evolutionary algorithm provides a superior approach for multi-objective metabolic modeling in microalgae.
  • * This method enhances decision-making capabilities in metabolic engineering for bioproduct optimization.
  • * The findings offer a valuable tool for advancing microalgae-based biotechnology.