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Updated: Oct 3, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

[Arterial calcifications of the hand: normal aging and the course in chronic dialysis patients]

E Fischer

    Der Radiologe
    |March 1, 1987
    PubMed

    Insights

    Arterial calcifications in the hand differ in patients on dialysis or with diabetic nephropathy. Finger-metacarpal arterial calcifications indicate a poor prognosis in these patients.

    Area of Science:

    • Vascular biology
    • Nephrology
    • Geriatric medicine

    Background:

    • Arterial calcifications typically progress distally in hands, sparing fingers until later life.
    • Patients undergoing maintenance dialysis exhibit altered arterial calcification patterns.
    • Diabetic nephropathy is associated with the most severe arterial calcifications.

    Purpose of the Study:

    • To investigate the progression and characteristics of arterial calcifications in specific patient populations.
    • To determine the prognostic significance of arterial calcifications in the finger-metacarpal region.

    Main Methods:

    • Observational study comparing arterial calcification patterns.
    • Analysis of patient data including dialysis status and diabetic nephropathy.
    • Radiographic assessment of calcification in the hand and finger-metacarpal regions.

    Main Results:

    • Arterial calcifications in maintenance dialysis patients start earlier and do not correlate with age.
    • Diabetic nephropathy patients show the most pronounced arterial calcifications.
    • Calcifications in the finger-metacarpal area are linked to unfavorable outcomes.

    Conclusions:

    • Hand arterial calcification patterns are significantly altered in patients with renal failure, particularly those on dialysis or with diabetic nephropathy.
    • Finger-metacarpal arterial calcifications serve as a negative prognostic indicator in these at-risk populations.

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