Glycemic Control for Type 2 Diabetes Mellitus Patients: A Systematic Review

Diabetes mellitus is a chronic metabolic disorder resulting in hyperglycemia and microvascular and macrovascular complications in individuals globally. Type 2 diabetes mellitus (T2DM) is highly prevalent and accounts for 90% of patients. Maintaining blood glucose concentration is essential to avoid severe complications. Glycemic control is the optimal serum glucose concentration in diabetic patients. It is necessary to identify factors affecting the glycemic control of patients to prevent control and complications. We conducted this systematic review to assess the factors affecting glycemic control among type 2 diabetes mellitus patients. Published literature between the years 2020 to 2022 was retrieved from PubMed, Science Direct, and Google Scholar using different combinations of keywords: T2DM, Glycemic control, Poor, Good, Adequate, Inadequate, Factors, Association, and Determinants. All original articles written in the English language with full-text available and the value of glycemic control defined were included. A total of 1866 studies were retrieved. After the title, abstract, screening, and full-text screening, 12 studies were eligible. The prevalence of poor glycemic control was high, and it ranged between 45.2% and 93% among the studies. The factors associated with glycemic control were stratified into four categories: personal or body-related, clinical, medication-related, and behavioral factors. There was a high prevalence of poor glycemic control in all included studies. The glycemic control was associated with various factors; some were related to the patient or medical conditions while others were related to the behavior of the patients or the medication administrated.