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Updated: Sep 3, 2025

Microfluidic Fabrication of Polymeric and Biohybrid Fibers with Predesigned Size and Shape
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Tailoring micro/nano-fibers for biomedical applications.

Bin Kong1, Rui Liu1, Jiahui Guo2,3

  • 1Department of Cardio-Thoracic Surgery, Institute of Translational Medicine, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, 210008, Nanjing, China.

Bioactive Materials
|July 27, 2022
PubMed
Summary

Nano/micro fibers offer enhanced properties like strength and surface area, driving innovation in biomedical applications. This review covers fabrication methods and uses in tissue engineering, drug delivery, and biosensors.

Keywords:
Biomedical fieldBioprintingElectrospinningMicrofluidic spinningNano/micro fibersNear field electrospinning

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Last Updated: Sep 3, 2025

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Area of Science:

  • Fiber science
  • Materials science
  • Biomedical engineering

Background:

  • Nano/micro fibers are gaining attention due to advanced manufacturing.
  • Their nano/micro-scale dimensions provide enhanced mechanical strength and high surface area.
  • These properties enable diverse applications in environmental, electronic, and biomedical fields.

Purpose of the Study:

  • To review recent advancements in nano/micro fiber fabrication strategies.
  • To explore the applications of nano/micro fibers in biomedical fields.
  • To discuss challenges and future perspectives in nano/micro fiber technology.

Main Methods:

  • Literature review of nano/micro fiber fabrication techniques.
  • Analysis of applications in tissue engineering, drug delivery, wound healing, and biosensors.
  • Discussion of fabrication and application challenges.

Main Results:

  • Various fabrication strategies for nano/micro fibers have been developed.
  • Nano/micro fibers show significant potential in biomedical applications.
  • Key applications include tissue engineering scaffolds, drug delivery systems, wound healing dressings, and biosensors.

Conclusions:

  • Nano/micro fibers possess unique properties suitable for advanced biomedical applications.
  • Continued research into fabrication and application is crucial.
  • Addressing current challenges will unlock future potential in the biomedical field.