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Updated: Sep 3, 2025
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Predictive Immune Modeling of Solid Tumors
Published on: February 25, 2020
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Techniques for Profiling the Cellular Immune Response and Their Implications for Interventional Oncology.
Tushar Garg1, Clifford R Weiss1, Rahul A Sheth2
1Division of Vascular and Interventional Radiology, Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Cancers
|July 27, 2022
Summary
Understanding the tumor microenvironment is key for cancer prognosis. This review details technologies for immune assessment, aiding clinical practice and research in cancer immunotherapy.
Area of Science:
- Oncology
- Immunology
- Radiology
Background:
- The tumor microenvironment, comprising various immune cells, influences cancer patient prognosis.
- Accurate assessment of the tumor microenvironment is crucial for effective cancer treatment, especially immunotherapies.
Purpose of the Study:
- To review technologies for evaluating the tumor microenvironment's immune contexture.
- To provide knowledge for interpreting and applying immune assessment data in clinical practice and research.
Main Methods:
- Review of current technologies for immune assessment of tumor microenvironment.
- Discussion of data analysis from immune assessment technologies.
Main Results:
- Image-guided tissue sampling is vital for cancer diagnosis and monitoring immunotherapy efficacy.
- Interventional radiologists are essential in evaluating patients undergoing immunotherapy.
Conclusions:
- This review equips readers to interpret and utilize immune assessment data.
- The information facilitates the design and application of immune assessment tools in clinical practice and future research.
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