Fluorescein Derivative Immobilized Optical Hydrogels: Fabrication and Its Application for Detection of H₂O₂

A novel fluorescein-based probe FLA-Boe was developed for detecting H₂O₂. Modified by 2-Bromomethylphenylboronic acid pinacol ester, FLA-Boe is a Fluorescein derivative with eminent photostability and remarkable H₂O₂ sensitivity and selectivity. FLA-Boe was utilized to synthesize hydrogel sensors in the manner of guest-host interaction by taking advantage of its aforementioned features. The hydrogel sensor can be used to detect H₂O₂ effectively in both flowing and static water environments with satisfactory performance. It is expected that this application may open a new page to develop a neoteric fluorescent property analysis method aiming at H₂O₂ detection.