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Sodium phosphate cotransporter 2a inhibitors: potential therapeutic uses

Jianxiang Xue1, Linto Thomas1, Jessica A Dominguez Rieg1,2

  • 1Department of Molecular Pharmacology and Physiology.

Current Opinion in Nephrology and Hypertension
|July 27, 2022
PubMed
Summary

Targeting sodium phosphate cotransporter 2a (Npt2a) offers a novel strategy for treating hyperphosphatemia in chronic kidney disease (CKD). Npt2a inhibition lowers plasma phosphate and parathyroid hormone, with potential cardiovascular benefits.

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