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Updated: Sep 3, 2025

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Orthotopic Left Lung Transplantation in Rats
Published on: July 3, 2025
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Left-to-right rotated single lung transplant.
Masayuki Chida1, Takashi Inoue1, Osamu Araki1
1Department of General Thoracic Surgery, Dokkyo Medical University, Japan.
Summary
This study details successful left-to-right rotated single lung transplants in two patients. The technique involves a specific U-shaped turn of the donor pulmonary artery to connect with the recipient
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Transplantation Medicine
Background:
- Single lung transplantation is a critical treatment for end-stage lung disease.
- Rotated lung transplants present unique surgical challenges, particularly regarding vascular anastomosis.
- Maintaining pulmonary artery patency is vital for graft survival.
Purpose of the Study:
- To describe a novel technique for left-to-right rotated single lung transplantation.
- To highlight the critical steps and potential pitfalls in this complex procedure.
Main Methods:
- Successful execution of left-to-right rotated single lung transplants in two patients.
- A specific U-shaped maneuver of the donor left pulmonary artery was employed.
- Anastomosis of the donor pulmonary artery to the recipient right pulmonary artery was performed anterior to the bronchus.
Main Results:
- The surgical procedure was successfully completed in both patients.
- The described technique facilitated the necessary vascular connection for rotated lung transplantation.
Conclusions:
- Left-to-right rotated single lung transplantation is feasible using this specific technique.
- Careful management of the pulmonary artery U-shaped turn is essential to prevent kinking and ensure graft viability.

