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The positive correlation between brachial-ankle pulse wave velocity and aortic diameter in Chinese patients with

Liping Li1, Wenhui Xie1, Qingqing Li1

  • 1Department of Geriatrics, Fujian Key Laboratory of Vascular Aging (Fujian Medical University), Fujian Institute of Geriatrics, Department of Cardiology, Fujian Heart Disease Center, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.

Journal of Clinical Hypertension (Greenwich, Conn.)
|July 27, 2022
PubMed

Insights

Brachial-ankle pulse wave velocity (baPWV) is linked to aortic diameter (AoD) in diabetic patients. Higher baPWV indicates increased arterial stiffness and a greater risk of aortic dilation, suggesting a potential target for cardiovascular disease prevention.

Area of Science:

  • Cardiology
  • Vascular Medicine
  • Diabetology

Background:

  • Aortic dilation increases cardiovascular disease risk.
  • Brachial-ankle pulse wave velocity (baPWV) reflects arterial stiffness and vascular aging.
  • Arterial stiffness is a significant risk factor for vascular diseases.

Purpose of the Study:

  • To investigate the correlation between baPWV and aortic diameter (AoD) in diabetic inpatients.
  • To identify factors associated with aortic dilation in this population.

Main Methods:

  • Retrospective analysis of 1294 diabetic patients' medical records.
  • Assessment of arterial stiffness using baPWV.
  • Measurement of AoD via echocardiography.

Main Results:

  • Both baPWV and AoD increased with age.
  • Independent predictors of AoD included age, blood pressure, cardiac dimensions, and baPWV.
  • The highest baPWV quartile was associated with an increased risk of aortic dilation compared to the lowest quartile.

Conclusions:

  • baPWV is independently and positively associated with AoD in diabetic patients.
  • baPWV may serve as a biomarker for aortic dilation risk.
  • Further research through prospective studies or clinical trials is warranted to explore interventions targeting arterial stiffness.

Keywords:
aortic diameterarterial stiffnessbrachial-ankle pulse wave velocitydiabetes

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