Evaluation of IOL power calculation with the Kane formula for pediatric cataract surgery
Olga Reitblat1,2, Sina Khalili3,4, Asim Ali3,4
1Department of Ophthalmology, Rabin Medical Center, 39 Jabotinski St, Petach Tikva, Israel.
Insights
The Kane formula demonstrates accuracy comparable to other methods for intraocular lens power calculation in pediatric cataract surgery. This study suggests the Kane formula is a valuable tool for improving IOL calculations in children.
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
- Biomedical Engineering
Background:
- Accurate intraocular lens (IOL) power calculation is crucial for visual outcomes in pediatric cataract surgery.
- Existing formulas may have varying degrees of accuracy in pediatric populations due to differences in ocular physiology.
Purpose of the Study:
- To evaluate the predictive accuracy of the Kane formula for IOL power calculation in pediatric patients.
- To compare the Kane formula's performance against established IOL calculation formulas.
Main Methods:
- Retrospective chart review of pediatric patients who underwent cataract surgery and IOL implantation.
- Comparison of prediction errors from the Kane formula with Barrett Universal II, Haigis, Hoffer Q, Holladay 1, and SRK/T formulas.
- Statistical analysis including standard deviation of prediction error and median/mean absolute errors.
Main Results:
- The Kane formula showed prediction error standard deviation comparable to other formulas (Kane: 1.38 D).
- No significant differences in median and mean absolute errors were found between the Kane formula and other tested formulas (p=0.099).
- The heteroscedastic statistical method was utilized for formula predictability evaluation in children.
Conclusions:
- The Kane formula is a noteworthy option for IOL power calculation in pediatric cataract surgery.
- It offers an additional method to enhance the accuracy of IOL power calculations in this age group.
- This study is the first to assess the Kane formula's efficacy in pediatric populations.
Purpose:
To assess the accuracy of the Kane formula for intraocular lens (IOL) power calculation in the pediatric population.
Methods:
The charts of pediatric patients who underwent cataract surgery with in-the-bag IOL implantation with one of two IOL models (SA60AT or MA60AC) between 2012 and 2018 in The Hospital for Sick Children, Toronto, Ontario, CanFada, were retrospectively reviewed. The accuracy of IOL power calculation with the Kane formula was evaluated in comparison with the Barrett Universal II (BUII), Haigis, Hoffer Q, Holladay 1, and Sanders-Retzlaff-Kraff Theoretical (SRK/T) formulas.
Results:
Sixty-two eyes of 62 patients aged 6.2 (IQR 3.2-9.2) years were included. The SD values of the prediction error obtained by Kane (1.38) were comparable with those by BUII (1.34), Hoffer Q (1.37), SRK/T (1.40), Holaday 1 (1.41), and Haigis (1.50), all p > 0.05. A significant difference was observed between the Hoffer Q and Haigis formulas (p = 0.039). No differences in the median and mean absolute errors were found between the Kane formula (0.54 D and 0.91 ± 1.04 D) and BUII (0.50 D and 0.88 ± 1.00 D), Hoffer Q (0.48 D and 0.88 ± 1.05 D), SRK/T (0.72 D and 0.97 ± 1.00 D), Holladay 1 (0.63 D and 0.94 ± 1.05 D), and Haigis (0.57 D and 0.98 ± 1.13 D), p = 0.099.
Conclusion:
This is the first study to investigate the Kane formula in pediatric cataract surgery. Our results place the Kane among the noteworthy IOL power calculation formulas in this age group, offering an additional means for improving IOL calculation in pediatric cataract surgery. The heteroscedastic statistical method was first implemented to evaluate formulas' predictability in children.
