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Contrast-enhanced mammography-guided biopsy: technical feasibility and first outcomes
R Alcantara1,2, M Posso3, M Pitarch4
1Radiology and Nuclear Medicine Department, Hospital del Mar, Parc de Salut Mar, Passeig Marítim de la Barceloneta, 25-29, 08003, Barcelona, Spain. ralcantara@psmar.cat.
European Radiology
|July 27, 2022
Summary
Contrast-enhanced mammography (CEM)-guided biopsy is a feasible procedure for enhancing breast lesions. This study found a high success rate (95.4%) with manageable complications, similar to MRI-guided biopsies.
Area of Science:
- Radiology
- Breast Imaging
- Interventional Radiology
Background:
- Contrast-enhanced mammography (CEM) utilizes iodinated contrast media and dual-energy acquisition to visualize enhancing lesions.
- Accurate biopsy guidance is crucial for diagnosing suspicious breast abnormalities detected via CEM.
Purpose of the Study:
- To assess the feasibility of performing contrast-enhanced mammography (CEM)-guided breast biopsies.
- To evaluate the procedural success, time, and complication rates of CEM-guided biopsies in a clinical setting.
Main Methods:
- Retrospective review of 64 patients undergoing CEM-guided biopsy for suspicious enhancing lesions between October 2019 and September 2021.
- Biopsies were performed using a stereotactic-based approach with vacuum-assisted devices.
- Feasibility endpoints included lesion visualization, clip placement, procedural time, and complications.
Main Results:
- A total of 66 lesions were biopsied with a high success rate of 95.4%.
- The median procedure time was 15 minutes, with a median of 2 acquisitions needed.
- Common complications included hematoma (27%) and vasovagal reaction (3.2%). Malignancy rate was 39.7%.
Conclusions:
- CEM-guided breast biopsy is a feasible and effective technique for diagnosing enhancing breast lesions.
- The success and complication rates are comparable to those reported for magnetic resonance-guided biopsies.
- CEM-guided biopsy offers a potentially widely available option for biopsy of enhancing-only lesions.
