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Perinatal stroke: management guideline
Eszter Vojcek1, István Seri1,2
11 Semmelweis Egyetem, Általános Orvostudományi Kar, I. Gyermekgyógyászati Klinika Budapest, Bókay J. u. 53-54., 1083 Magyarország.
Orvosi Hetilap
|July 27, 2022
Summary
Perinatal stroke, a heterogeneous neurological syndrome, can lead to chronic neurological deficits. This review outlines diagnostic and therapeutic guidelines for perinatal stroke, impacting approximately 1 in 1100 births.
Area of Science:
- Neurology
- Pediatrics
- Neonatology
Background:
- Perinatal stroke is a heterogeneous neurological syndrome resulting from brain injury with long-term chronic neurological outcomes.
- It encompasses perinatal arterial ischemic stroke, sinus thrombosis, and hemorrhagic stroke.
- Conditions presenting with motor asymmetry between 4-8 months are presumed to be of perinatal origin.
Purpose of the Study:
- To establish guidelines for the diagnosis and therapy of perinatal stroke.
- To review recent studies on risk factors, MRI findings, and outcomes of perinatal stroke.
Main Methods:
- Literature review of recent studies on perinatal stroke.
- Analysis of risk factors, MRI findings, and patient outcomes.
- Development of diagnostic and therapeutic recommendations.
Main Results:
- The incidence of perinatal stroke is approximately 1 in 1100 births.
- While 40% of affected newborns develop without symptoms, the remaining experience long-term neurological deficits.
- Neurological outcomes include cerebral palsy, epilepsy, cognitive impairment, behavioral disorders, speech problems, and sensory deficits.
Conclusions:
- Perinatal stroke is a significant cause of long-term neurological disability in children.
- Early diagnosis and appropriate management are crucial for improving outcomes.
- Further research is needed to better understand risk factors and optimize therapeutic strategies.
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